Evaluation of GVHD And oral mucositis in patients submitted to HSCT at the STMO-CHC of UFPR

Oral graft-versus-host disease (GVHD) and oral mucositis (OM) are important complications of hematopoietic stem cell transplantation (HSCT) that significantly impact the patient's quality life. In this context, study aimed to evaluate profile patients undergoing allogeneic HSCT, assessing GVHD OM occurrence. Data from medical records underwent HSCT between 2019 2021 were collected. Patients over 18 years old, with diseases or conditions requiring included. A clinical examination was performed occurrence OM. total 47 evaluated which 34.04% developed GVHD, these 81.25% have had involvement. As for OM, it affected 82.97% patients, grades 3 4 being more detected. The most frequent previous acute myeloid leukemia, received a related type transplant (84.61%), fully compatible (53.84%), bone marrow as source cells (53.84%). Most myeloablative conditioning regimen (69.23%). Cyclosporine immunosuppressive agent used prevention associated methotrexate (76.92%). debilitating can compromise general health overall survival. Early diagnosis is quick start treatment reduce on prognosis.